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Best Pract Res Clin Endocrinol Metab

Sleep deprivation increases ghrelin (the hunger hormone), reduces leptin (the satiety hormone), increases insulin resistance, and promotes cortisol-driven visceral fat storage

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No weird side effects, just steady and noticeable benefits

And we think of years lived with obesity now like smoking years lived with tobacco we're starting to think of years lived with obesity not so much to change my treatment but to render the risk estimate that you have

Lipotoxicity and diabetic nephropathy: novel mechanistic insights and therapeutic opportunities